Chronic inflammation can cause several diseases and conditions, including some cancers, obesity, asthma, rheumatoid arthritis, atherosclerosis, ischemic heart disease, and ulcerative colitis. Despite the fact that several types of research were performed on the prevention and treatment of inflammation-related diseases, the overall incidence has not changed significantly. Moreover, the exact mechanism underlying the process of these diseases still remains hidden. In humans, inflammation is considered a common feature of these diseases, which might be responsible for the dysfunction or dysregulation of specific cells and tissues that contribute to the origin and development of the disease. Due to the fact that chronic inflammation may play crucial roles in disease initiation, a broad spectrum of preclinical and clinical studies had been investigated to reveal the mechanisms of chronic inflammation in the biological system and to develop drugs to overcome inflammation-mediated diseases. Natural products from the herbal remedy, medicinal plants, functional foods, and their constituent have been used for the treatment of various diseases including cancer from ancient times to recent days; increasing emphasis has been focused on the research on traditional medicine: many herbs and medicinal plants. This requires new approaches to overcome inflammation-mediated diseases and thus natural products could be efficacious sources for the prevention and treatment of these diseases.
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